Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144800 | 0.82 | MAOA (0.56) | MAOAMAOBKDM4ENOTUMKDM4C | |
| SCHEMBL28591105 | 0.82 | MAOA (0.59) | MAOAMAOBKDM4ENOTUMKDM4C | |
| SCHEMBL28201512 | 0.81 | MAOA (0.54) | MAOAMAOBKDM4ENOTUMPDK1 | |
| SCHEMBL26170012 | 0.81 | MAOA (0.58) | MAOAMAOBKDM4ENOTUMKDM4C | |
| SCHEMBL3436324 | 0.81 | NPC1 (0.50) | MAOAMAOBKDM4ENOTUMMAPT | |
| Hydrochloric Acid SCHEMBL28856319 | 0.79 | MAOA (0.53) | MAOAMAOBKDM4ENOTUMPDK1 | |
| SCHEMBL1144873 | 0.78 | MAOA (0.55) | MAOAMAOBKDM4ENOTUMMAPT | |
| Formic Acid SCHEMBL30427064 | 0.76 | MAOA (0.50) | MAOAMAOBKDM4ENOTUMPDK1 | |
| SCHEMBL21573033 | 0.73 | ALDH1A1 (0.59) | KDM4EATMMAPTALDH1A1NPC1 | |
| SCHEMBL27750270 | 0.73 | KMT2A (0.46) | ALDH1A1NPC1RAB9AKDM1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910139-A | Preparation method and application of mitochondrial fluorescence coloring agent 3-heteroaryl substituted-2H-indazole derivatives | UNIV SICHUAN | 2015-09-16 | — | — | CN | disclosed |