Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201512 | 0.94 | MAOA (0.54) | MAOAMAOBKDM4EALDH1A1BRD4 | |
| Hydrochloric Acid SCHEMBL28856319 | 0.92 | MAOA (0.53) | MAOAMAOBKDM4EALDH1A1BRD4 | |
| Formic Acid SCHEMBL30423402 | 0.83 | KDM4E (0.42) | MAOAMAOBKDM4ENOTUMMKNK1 | |
| SCHEMBL9989118 | 0.81 | KDM4E (0.57) | MAOAMAOBKDM4EALDH1A1BRD4 | |
| SCHEMBL28591105 | 0.80 | MAOA (0.59) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1144800 | 0.80 | MAOA (0.56) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL26170012 | 0.78 | MAOA (0.58) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1144873 | 0.76 | MAOA (0.55) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28037046 | 0.76 | MAOA (0.52) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30177194 | 0.75 | HPGDS (0.40) | MAOAMAOBKDM4EALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4433457-A1 | HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME | Rgenta Therapeutics, Inc. (US) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023092098-A1 | HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |