Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28856319 | 0.98 | MAOA (0.53) | MAOAMAOBKDM4EALDH1A1BRD4 | |
| Formic Acid SCHEMBL30427064 | 0.94 | MAOA (0.50) | MAOAMAOBKDM4EALDH1A1BRD4 | |
| SCHEMBL9989118 | 0.87 | KDM4E (0.57) | MAOAMAOBKDM4EALDH1A1BRD4 | |
| SCHEMBL1144800 | 0.85 | MAOA (0.56) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28591105 | 0.85 | MAOA (0.59) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL26170012 | 0.83 | MAOA (0.58) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1144873 | 0.81 | MAOA (0.55) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28037046 | 0.81 | MAOA (0.52) | MAOAMAOBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30177194 | 0.80 | HPGDS (0.40) | MAOAMAOBKDM4EALDH1A1BRD4 | |
| SCHEMBL12073303 | 0.79 | MAP2K4 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551593-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-105451737-B | Medical composition and its use and described pharmaceutical composition are used for the application process practised contraception on demand | 拜耳医药股份有限公司 | 2018-04-10 | — | — | CN | disclosed |