Ethylene

Ethylene

SCHEMBL28037152

C=C.Fc1ccc(F)c(F)c1F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
BCHE P06276 1/20 0.33
ALDH1A1 P00352 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
CA3 P07451 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45430 0.91 CES2 (0.53) CES2CES1BCHEALDH1A1GPR84
SCHEMBL3975406 0.87 CES2 (0.50) CES2CES1BCHEALDH1A1GPR84
SCHEMBL11355080 0.87 CES2 (0.50) CES2CES1BCHEALDH1A1GPR84
Ammonia Solution, Strong SCHEMBL3047305 0.87 CES2 (0.50) CES2CES1BCHEALDH1A1GPR84
Hydrazine SCHEMBL3793747 0.83 CES2 (0.48) CES2CES1BCHEALDH1A1GPR84
Butadiene SCHEMBL9775438 0.82 CES2 (0.42) CES2CES1ALDH1A1
SCHEMBL489680 0.79 CES2 (0.40) CES2CES1DAO
SCHEMBL5716618 0.77 CTSL (0.44) CES2CES1BCHEALDH1A1GPR84
SCHEMBL7173696 0.77 CES2 (0.43) CES2CES1BCHEALDH1A1GPR84
SCHEMBL146632 0.73 RIPK1 (0.36) CES2CES1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105061682-A Preparation method and application of hydrogen bond crosslinked polyolefin UNIV BEIJING CHEMICAL 2015-11-18 CN disclosed