Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657784 | 0.92 | SIGMAR1 (0.72) | SIGMAR1ALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL1499551 | 0.90 | PDE4B (0.56) | SIGMAR1ALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL27792610 | 0.85 | ALDH1A1 (0.51) | SIGMAR1ALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL8783271 | 0.84 | SIGMAR1 (0.57) | SIGMAR1ALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL27951641 | 0.84 | ALDH1A1 (0.65) | SIGMAR1ALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL30098865 | 0.84 | ALDH1A1 (0.73) | ALDH1A1GAAMAPTL3MBTL1KMT2A | |
| SCHEMBL9491894 | 0.84 | GAA (0.73) | SIGMAR1ALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL11756934 | 0.84 | GAA (0.73) | SIGMAR1ALDH1A1GAAMAPTL3MBTL1 | |
| SCHEMBL6361446 | 0.84 | GAA (0.73) | ALDH1A1GAAMAPTL3MBTL1KMT2A | |
| SCHEMBL1499442 | 0.83 | MTNR1B (0.54) | ALDH1A1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073725-A | Pyrazolyl-ureas as kinase inhibitors | RESPIVERT LTD | 2015-11-18 | — | — | CN | disclosed |