Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCKBR | P32239 | 2/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28333618 | 0.87 | CHRM1 (0.56) | OPRK1CNR1NTSR1PDE4DCHRM1 | |
| SCHEMBL28536668 | 0.86 | GABRA1 (0.57) | OPRK1CNR1NTSR1PDE4DCHRM1 | |
| SCHEMBL27689076 | 0.85 | OPRK1 (0.39) | OPRK1CNR1NTSR1PDE4DCHRM1 | |
| SCHEMBL27533159 | 0.84 | LMNA (0.59) | CHRM1LMNACCNE2CCNE1CDK2 | |
| SCHEMBL27390735 | 0.84 | GABRA1 (0.50) | OPRK1CNR1NTSR1PDE4DCHRM1 | |
| SCHEMBL27304815 | 0.82 | CNR1 (0.38) | OPRK1CNR1NTSR1PDE4DCHRM1 | |
| SCHEMBL28150316 | 0.81 | CNR1 (0.39) | OPRK1CNR1NTSR1PDE4DCHRM1 | |
| SCHEMBL27717603 | 0.81 | LMNA (0.60) | OPRK1PDE4DCHRM1ALDH1A1MEN1 | |
| SCHEMBL27663056 | 0.79 | LMNA (0.47) | OPRK1CNR1NTSR1PDE4DCHRM1 | |
| SCHEMBL10672472 | 0.77 | CHRM1 (0.53) | OPRK1CNR1NTSR1PDE4DCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290353-A | Preparation method of stable isotope labeled diazepam | 司法鉴定科学研究院 | 2024-07-05 | — | — | CN | claimed |
| CN-110579546-B | Method for measuring alprazolam tablet related substances by high performance liquid chromatography | 北京悦康科创医药科技股份有限公司 | 2022-05-03 | — | — | CN | claimed |
| CN-118290353-A | Preparation method of stable isotope labeled diazepam | 司法鉴定科学研究院 | 2024-07-05 | — | — | CN | disclosed |
| CN-118290353-A | Preparation method of stable isotope labeled diazepam | 司法鉴定科学研究院 | 2024-07-05 | — | — | CN | disclosed |
| CN-112500359-B | Preparation method of lorazepam intermediate | 华中药业股份有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-110579546-B | Method for measuring alprazolam tablet related substances by high performance liquid chromatography | 北京悦康科创医药科技股份有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-112500359-A | Preparation method of lorazepam intermediate | 华中药业股份有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-110579546-A | Method for measuring alprazolam tablet related substances by high performance liquid chromatography | 北京悦康科创医药科技股份有限公司 | 2019-12-17 | — | — | CN | disclosed |
| CN-104961692-A | Improved preparation method of 7-chlorin-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepine-2-keto-4-oxide | HUAZHONG PHARMACEUTICAL CO LTD | 2015-10-07 | — | — | CN | disclosed |