Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15122274 | 0.85 | NOTUM (0.51) | NOTUMS1PR1PDE3BPDE3A | |
| SCHEMBL28037158 | 0.85 | NCF1 (0.45) | NOTUM | |
| SCHEMBL250177 | 0.84 | NOTUM (0.47) | NOTUMAR | |
| SCHEMBL28037155 | 0.84 | ALDH1A1 (0.45) | NOTUMPDE3BPDE3AAR | |
| SCHEMBL3532873 | 0.83 | NOTUM (0.48) | NOTUMAR | |
| SCHEMBL25194643 | 0.76 | ALDH1A1 (0.59) | NOTUM | |
| SCHEMBL249224 | 0.76 | NOTUM (0.50) | NOTUMS1PR1PDE3BPDE3A | |
| SCHEMBL3849954 | 0.76 | NOTUM (0.54) | NOTUMS1PR1PDE3BPDE3A | |
| SCHEMBL30336413 | 0.76 | ALDH1A1 (0.59) | NOTUM | |
| SCHEMBL1929368 | 0.76 | ALDH1A1 (0.59) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061326-A | Pyridazinone derivatives as well as preparation method and application thereof | SICHUAN BAILI PHARMACEUTICAL CO LTD | 2015-11-18 | — | — | CN | disclosed |