Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29036480 | 1.00 | TSHR (0.50) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL28344893 | 0.94 | TSHR (0.51) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL28256300 | 0.88 | LMNA (0.47) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL27491439 | 0.86 | TSHR (0.48) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL28268654 | 0.84 | TSHR (0.43) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL351793 | 0.82 | MEN1 (0.51) | TSHRALDH1A1TDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1093412 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNATDP1 | |
| SCHEMBL4094428 | 0.80 | FAAH (0.49) | TSHRALDH1A1LMNATP53TDP1 | |
| SCHEMBL868458 | 0.80 | TSHR (0.53) | TSHRALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL5174859 | 0.80 | TSHR (0.53) | TSHRALDH1A1LMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377811-A | Cyanostilbenes | ROLIC AG | 2016-03-02 | — | — | CN | disclosed |