Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | USP7 | Q93009 | 2/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17578990 | 0.79 | ALK (0.43) | ALKALDH1A1LMNAMAPTHTT | |
| Hydrochloric Acid SCHEMBL27996151 | 0.78 | ALK (0.42) | ALKALDH1A1LMNAMAPTHTT | |
| SCHEMBL28038009 | 0.77 | PTGES (0.45) | ALKALDH1A1LMNAGAAHTT | |
| SCHEMBL27769709 | 0.77 | ALK (0.41) | ALKALDH1A1LMNAP4HBGAA | |
| Ammonia Solution, Strong SCHEMBL5655416 | 0.76 | TAAR1 (0.46) | ALDH1A1LMNAHTT | |
| SCHEMBL16224287 | 0.74 | BCHE (0.45) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL9161994 | 0.72 | NR4A2 (0.53) | ALDH1A1LMNAMAPT | |
| SCHEMBL20073053 | 0.71 | HTT (0.49) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL1557613 | 0.71 | TNF (0.42) | ALDH1A1LMNAHTTTSHRCHEK1 | |
| SCHEMBL28140817 | 0.71 | ALK (0.49) | ALKALDH1A1LMNAP4HBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143228-B | [1,2,4] triazol [4,3 a] pyridine derivatives, its preparation method or its in application pharmaceutically | 江苏豪森药业集团有限公司 | 2017-07-21 | — | — | CN | disclosed |
| CN-105143228-A | [1,2,4]triazol[4,3-a]pyridine derivate, preparation method therefor or medical application thereof | JIANGSU HANSOH PHARMACEUTICAL | 2015-12-09 | — | — | CN | disclosed |