Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167511 | 0.82 | CRHBP (0.44) | MAPTMEN1KMT2ATDP1CRHBP | |
| SCHEMBL358629 | 0.81 | MAPT (0.45) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL27769710 | 0.80 | PTGES (0.45) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL28038007 | 0.77 | ALK (0.46) | ALKMAPTHTTALDH1A1MEN1 | |
| SCHEMBL28468025 | 0.76 | EGFR (0.42) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL9248753 | 0.76 | TSHR (0.42) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL358123 | 0.75 | EGFR (0.42) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL20319134 | 0.75 | CTSB (0.42) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL1557518 | 0.75 | LMNA (0.41) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL30074880 | 0.72 | PTGES (0.49) | MAPTHTTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102796099-A | Imidazoquinolines as lipid kinase inhibitors | NOVARTIS AG | 2012-11-28 | — | — | CN | disclosed |
| CN-101495477-A | Imidazoquinolines as lipid kinase inhibitors | NOVARTIS AG (CH) | 2009-07-29 | — | — | CN | disclosed |