Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 8/20 | 0.80 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.80 |
| ▸ | BCL2 | P10415 | 6/20 | 0.80 |
| ▸ | RPA1 | P27694 | 5/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MARS1 | P56192 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28180312 | 0.89 | MDM2 (0.81) | MDM2MCL1BCL2RPA1L3MBTL1 | |
| SCHEMBL3139245 | 0.79 | RPA1 (1.00) | MDM2MCL1BCL2RPA1L3MBTL1 | |
| SCHEMBL9056282 | 0.79 | RPA1 (0.90) | MDM2MCL1BCL2RPA1L3MBTL1 | |
| SCHEMBL20785644 | 0.78 | PPP1CA (0.68) | MDM2MCL1BCL2RPA1L3MBTL1 | |
| SCHEMBL28038232 | 0.78 | BCL2 (0.65) | MDM2MCL1BCL2RPA1SMN1; SMN2 | |
| SCHEMBL695352 | 0.76 | RPA1 (1.00) | MDM2MCL1BCL2RPA1L3MBTL1 | |
| SCHEMBL1514335 | 0.75 | RPA1 (0.80) | MDM2MCL1BCL2RPA1L3MBTL1 | |
| SCHEMBL4500796 | 0.75 | L3MBTL1 (1.00) | MDM2MCL1BCL2RPA1L3MBTL1 | |
| SCHEMBL1514681 | 0.75 | L3MBTL1 (0.89) | RPA1L3MBTL1SMN1; SMN2PPP1CAMEN1 | |
| SCHEMBL28038265 | 0.75 | MDM2 (0.82) | MDM2MCL1BCL2RPA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061315-A | 1, 5-diphenylpyrazole-3-carboxylic acid compounds and application thereof | UNIV DALIAN TECH | 2015-11-18 | — | — | CN | claimed |
| CN-105061315-B | 1, 5-diphenylpyrazole-3-carboxylic acid compounds and application thereof | 大连理工大学 | 2017-10-24 | — | — | CN | disclosed |
| CN-105061315-A | 1, 5-diphenylpyrazole-3-carboxylic acid compounds and application thereof | UNIV DALIAN TECH | 2015-11-18 | — | — | CN | disclosed |