Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.62 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.56 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.56 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491543 | 0.92 | GNAI3 (0.64) | SLC6A5GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL4647979 | 0.92 | GNAI3 (0.64) | SLC6A5GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL4647986 | 0.92 | GNAI3 (0.64) | SLC6A5GNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL15798737 | 0.82 | GNAI3 (0.84) | SLC6A5GNAI3GNAO1GNAI1DPP8 | |
| SCHEMBL15798735 | 0.82 | GNAI3 (0.84) | SLC6A5GNAI3GNAO1GNAI1DPP8 | |
| SCHEMBL17084282 | 0.81 | NOD1 (0.68) | SLC6A5GNAI3GNAO1GNAI1 | |
| SCHEMBL17084283 | 0.81 | NOD1 (0.68) | SLC6A5GNAI3GNAO1GNAI1 | |
| SCHEMBL22471671 | 0.80 | FAAH (0.55) | SLC6A5FAAHMEN1KMT2ACYP1A2 | |
| SCHEMBL4815645 | 0.80 | FAAH (0.55) | SLC6A5FAAHMEN1KMT2ACYP1A2 | |
| SCHEMBL20414960 | 0.80 | SLC6A5 (0.70) | SLC6A5FAAHMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188673-A | Formulations and carrier systems including compound interactive domains | UNIV PITTSBURGH | 2015-12-23 | — | — | CN | disclosed |