SCHEMBL28038488

SCHEMBL28038488

O=C(O)CC(O)(C(=O)O)c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.46
ESR2 Q92731 5/20 0.46
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 3/20 0.46
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42
CA2 P00918 2/20 0.42
CAMK2A Q9UQM7 1/20 0.42
MIF P14174 1/20 0.41
SLC13A5 Q86YT5 2/20 0.39
KIF11 P52732 2/20 0.39
BLM P54132 1/20 0.38
TYR P14679 2/20 0.37
ESRRG P62508 2/20 0.37
LMNA P02545 1/20 0.37
AR P10275 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8018070 0.85 CYP2C19 (0.57) ALDH1A1CYP2C19HIF1AMIFSLC13A5
SCHEMBL18130270 0.82 CYP2C19 (0.46) ALDH1A1CYP2C19HIF1AMIFSLC13A5
SCHEMBL2823398 0.82 ESR1 (0.43) ESR1ESR2ALDH1A1CYP3A4HIF1A
SCHEMBL28132726 0.78 CYP2C19 (0.41) ALDH1A1CYP3A4CYP2C19HIF1AMIF
SCHEMBL472287 0.78 SLC2A1 (0.50) ALDH1A1CYP2C19HIF1ASLC13A5HPGD
SCHEMBL11510565 0.78 ESR2 (0.56) ESR1ESR2ALDH1A1CYP3A4CYP2C19
SCHEMBL4214180 0.78 CA2 (0.48) ESR1ESR2ALDH1A1CYP3A4CYP2C19
SCHEMBL28305537 0.77 CYP2C19 (0.48) ESR1ESR2ALDH1A1CYP3A4CYP2C19
Citric Acid SCHEMBL2169490 0.77 ALDH1A1 (0.68) ESR1ESR2ALDH1A1CYP3A4CA2
SCHEMBL2291379 0.76 MIF (0.60) ESR1ESR2ALDH1A1CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105288096-B Medicine for treating whelk 上海资医堂生物科技有限公司 2021-04-02 CN disclosed
CN-105380051-B A kind of anti-alcohol and liver-protection beverage and preparation method thereof 九饮堂生物科技有限公司 2018-10-16 CN disclosed
CN-105380051-A Beverage capable of dispelling alcohol effect and protecting liver and preparation method of beverage QINGHAI GANLUYIN BIOTECHNOLOGY CO LTD 2016-03-09 CN disclosed
CN-105288096-A Acne treatment drug SHANGHAI CIEIANG BIOTECHNOLOGY CO LTD 2016-02-03 CN disclosed