Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418659 | 0.87 | PIN1 (0.58) | PIN1KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL4708943 | 0.85 | PIN1 (0.53) | PIN1KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL28049874 | 0.81 | HRH3 (0.52) | PIN1KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL8983209 | 0.81 | PDGFRB (0.60) | KDM4EALDH1A1RAB9AHPGDFLT3 | |
| SCHEMBL30073611 | 0.79 | PDGFRB (0.56) | KDM4EALDH1A1HSD17B10HPGDDAO | |
| SCHEMBL4265956 | 0.79 | PDGFRB (0.56) | KDM4EALDH1A1HSD17B10HPGDDAO | |
| SCHEMBL826338 | 0.77 | FLT3 (0.51) | PIN1KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL28761709 | 0.74 | DAO (0.50) | DAOPDGFRBPDGFRACA2HRH4 | |
| SCHEMBL10242689 | 0.74 | PIN1 (0.74) | PIN1KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL3411403 | 0.73 | DAO (0.50) | PIN1KDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392787-A | Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN LA ROCHE | 2016-03-09 | — | — | CN | disclosed |