Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 4/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3411403 | 0.87 | DAO (0.50) | PIN1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL28038745 | 0.87 | PIN1 (0.54) | PIN1KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL4708943 | 0.85 | PIN1 (0.53) | PIN1KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL5155719 | 0.81 | SMAD3 (0.57) | FLT3PDGFRBPDGFRAHRH4 | |
| SCHEMBL3419450 | 0.81 | PDGFRB (0.60) | KDM4EALDH1A1RAB9AHPGDFLT3 | |
| SCHEMBL3414863 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDDAO | |
| SCHEMBL3412727 | 0.80 | F7 (0.58) | KDM4EALDH1A1RAB9ASMN1; SMN2DAO | |
| SCHEMBL3381954 | 0.80 | FLT3 (0.48) | FLT3POLBNPC1HRH4MEN1 | |
| SCHEMBL6264258 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10RAB9AHPGD | |
| SCHEMBL10969990 | 0.80 | DAO (0.58) | PIN1KDM4EALDH1A1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149551-A1 | N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |
| EP-0512350-A2 | Indole derivatives | MERCK PATENT GmbH (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |