Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | DDO | Q99489 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418659 | 0.87 | PIN1 (0.58) | DAOFLT3PIN1RXFP1CA12 | |
| SCHEMBL4707550 | 0.83 | KDM4E (0.52) | DAODDOFLT3MAPTRXFP1 | |
| SCHEMBL3420585 | 0.81 | FLT3 (0.54) | FLT3MAPTRXFP1HSD17B10KDM4E | |
| SCHEMBL3418189 | 0.80 | ALOX15 (0.52) | DAOFLT3HSD17B10KDM4EMEN1 | |
| SCHEMBL3381701 | 0.80 | HRH4 (0.43) | MAPTKDM4E | |
| SCHEMBL3414920 | 0.80 | DAO (0.50) | DAODDOFLT3PIN1HSD17B10 | |
| SCHEMBL1833251 | 0.77 | KDM4E (0.55) | DAODDOFLT3MAPTHSD17B10 | |
| SCHEMBL31017884 | 0.74 | PIN1 (0.74) | DAODDOFLT3PIN1MAPT | |
| SCHEMBL1144688 | 0.74 | PIN1 (0.74) | DAODDOFLT3PIN1MAPT | |
| SCHEMBL112135 | 0.74 | GPR35 (0.55) | DAODDOCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149551-A1 | N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |