Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418659 | 0.85 | PIN1 (0.58) | PIN1FLT3ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28038745 | 0.85 | PIN1 (0.54) | PIN1FLT3ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9239615 | 0.83 | FLT3 (0.52) | FLT3ALDH1A1KDM4EHSD17B10RAB9A | |
| SCHEMBL6586200 | 0.80 | KDM4E (0.50) | FLT3ALDH1A1KDM4EHSD17B10RAB9A | |
| SCHEMBL826338 | 0.79 | FLT3 (0.51) | PIN1FLT3ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL214096 | 0.75 | RAB9A (0.72) | PIN1FLT3ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31310313 | 0.75 | RAB9A (0.72) | PIN1FLT3ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL19178802 | 0.75 | EHMT2 (0.50) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL14845690 | 0.75 | PIN1 (0.62) | PIN1FLT3ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7352325 | 0.73 | AXL (0.63) | FLT3ALDH1A1KDM4ERAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625129-B1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | BAYER HEALTHCARE AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| EP-1625129-A1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | Bayer HealthCare AG (DE) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004099212-A1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | BAYER HEALTHCARE AG (DE) | 2004-11-18 | — | — | WO | disclosed |