SCHEMBL28039358

SCHEMBL28039358

[CH2]CNc1ccccc1-c1ccccc1Br

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
MAPK1 P28482 2/20 0.40
BCHE P06276 1/20 0.37
CES1 P23141 1/20 0.37
TAAR1 Q96RJ0 2/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CXCR2 P25025 1/20 0.33
MAPK14 Q16539 1/20 0.32
PBRM1 Q86U86 1/20 0.32
IDO1 P14902 1/20 0.32
LMNA P02545 1/20 0.32
KDM4E B2RXH2 2/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
MPI P34949 1/20 0.31
DCUN1D1 Q96GG9 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28039640 0.77 ALDH1A1 (0.40) ALDH1A1MAPK1CES1LMNAKDM4E
SCHEMBL28039374 0.76 DPP4 (0.42) ALDH1A1KMT2AIDO1LMNAMAPT
SCHEMBL28039342 0.75 ALDH1A1 (0.47) ALDH1A1KMT2AL3MBTL1LMNAKDM4E
SCHEMBL28039653 0.73 DPP4 (0.48) ALDH1A1TAAR1KMT2AMAPT
SCHEMBL12525076 0.72 ALDH1A1 (0.44) ALDH1A1MAPK1TAAR1KMT2AL3MBTL1
SCHEMBL358976 0.72 ALDH1A1 (0.67) ALDH1A1MAPK1TAAR1KMT2AL3MBTL1
SCHEMBL31295703 0.72 ALDH1A1 (0.67) ALDH1A1MAPK1TAAR1KMT2AL3MBTL1
SCHEMBL28039658 0.72 HTR7 (0.45) ALDH1A1MAPK1L3MBTL1LMNAKDM4E
SCHEMBL28237947 0.70 MAPT (0.53) ALDH1A1MAPK1KMT2AL3MBTL1CXCR2
SCHEMBL31465796 0.69 ALDH1A1 (0.63) ALDH1A1MAPK1BCHECES1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017312-A Preparation method of beta-aminoethyl phosphono derivative UNIV SOOCHOW 2015-11-04 CN disclosed