SCHEMBL28039374

SCHEMBL28039374

[CH2]CNc1ccccc1-c1ccccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.42
CYP2A6 P11509 1/20 0.40
PTPRC P08575 1/20 0.39
DHODH Q02127 2/20 0.37
MAPT P10636 1/20 0.36
IDO1 P14902 1/20 0.36
NPC1 O15118 1/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
MAOB P27338 2/20 0.34
POLB P06746 1/20 0.34
PLA2G7 Q13093 1/20 0.34
CHRM3 P20309 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3168264 0.83 MAPT (0.48) MAPTIDO1HPGDSMN1; SMN2KMT2A
SCHEMBL3908445 0.80 POLB (0.44) DPP4CYP2A6PTPRCDHODHMAPT
SCHEMBL6862522 0.72 CYP2A6 (0.44) DPP4CYP2A6PTPRCDHODHMAPT
SCHEMBL671133 0.72 CYP2A6 (0.67) DPP4CYP2A6PTPRCIDO1NPC1
SCHEMBL29883244 0.72 CYP2A6 (0.67) DPP4CYP2A6PTPRCIDO1NPC1
SCHEMBL29802156 0.72 CYP2A6 (0.67) DPP4CYP2A6PTPRCIDO1NPC1
Hydrogen Sulfide SCHEMBL8574751 0.69 CYP2A6 (0.63) DPP4CYP2A6PTPRCIDO1NPC1
Hydrogen Sulfide SCHEMBL9195473 0.69 CYP2A6 (0.63) DPP4CYP2A6PTPRCIDO1NPC1
Ammonia Solution, Strong SCHEMBL735046 0.69 CYP2A6 (0.63) DPP4CYP2A6PTPRCIDO1NPC1
SCHEMBL28823485 0.69 QPCT (0.48) HPGDLMNAMAOBCHRM3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017312-A Preparation method of beta-aminoethyl phosphono derivative UNIV SOOCHOW 2015-11-04 CN disclosed