Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705879 | 0.91 | MAPK1 (0.31) | — | |
| SCHEMBL703961 | 0.91 | MAPK1 (0.31) | — | |
| SCHEMBL713408 | 0.89 | MAPK1 (0.30) | NR1H2NR1H3 | |
| SCHEMBL705747 | 0.87 | MAPK1 (0.33) | ESR1TSHR | |
| SCHEMBL707830 | 0.84 | LTA4H (0.35) | PTGS2LTA4HNR1H2NR1H3TSHR | |
| SCHEMBL704923 | 0.82 | LTA4H (0.34) | PTGS2LTA4HNR1H2NR1H3TSHR | |
| SCHEMBL875722 | 0.81 | LTA4H (0.38) | PTGS2LTA4HTSHRSOAT1PCSK9 | |
| SCHEMBL706547 | 0.81 | MAPK1 (0.32) | — | |
| SCHEMBL2655578 | 0.79 | LTA4H (0.37) | PTGS2LTA4HTSHRSOAT1PCSK9 | |
| SCHEMBL7529688 | 0.79 | LTA4H (0.37) | PTGS2LTA4HTSHRSOAT1PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107879960-A | For transmitting the lipid and lipid composition of active component | 诺华股份有限公司 | 2018-04-06 | — | — | CN | disclosed |
| CN-105164102-B | Lipids and lipid compositions for delivery of active ingredients | 诺华股份有限公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-105164102-A | Lipids and lipid compositions for delivery of active ingredients | NOVARTIS AG | 2015-12-16 | — | — | CN | disclosed |