Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234663 | 0.78 | ALDH1A1 (0.43) | POLBALDH1A1LMNAMEN1MAPT | |
| SCHEMBL27698740 | 0.73 | ALDH1A1 (0.40) | POLBALDH1A1LMNAMEN1MAPT | |
| SCHEMBL15224143 | 0.73 | ALDH1A1 (0.65) | POLBALDH1A1LMNAMEN1MAPT | |
| Hydrochloric Acid SCHEMBL28813665 | 0.73 | ALDH1A1 (0.40) | POLBALDH1A1LMNAMEN1MAPT | |
| SCHEMBL7762978 | 0.72 | HPGD (0.63) | ALDH1A1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL771653 | 0.70 | — | — | |
| SCHEMBL26433884 | 0.69 | L3MBTL1 (0.52) | POLBALDH1A1LMNAMEN1MAPT | |
| SCHEMBL15014507 | 0.69 | L3MBTL1 (0.52) | POLBALDH1A1LMNAMEN1MAPT | |
| SCHEMBL15158187 | 0.68 | HSD11B1 (0.42) | KMT2AL3MBTL1 | |
| SCHEMBL27980793 | 0.68 | CHRNB2 (0.50) | ALDH1A1LMNAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408331-A | Triazolopyridines as thrombin inhibitors for the treatment of thromboembolic disorders | Bayer Pharma AG | 2016-03-16 | — | — | CN | disclosed |