Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3185582 | 0.86 | PBRM1 (0.55) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL7048349 | 0.82 | ACHE (0.58) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL12164013 | 0.81 | PARP1 (0.60) | NPC1POLBACHESMN1; SMN2RAB9A | |
| SCHEMBL6153239 | 0.80 | ALDH1A1 (0.49) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL9559865 | 0.79 | PARP1 (0.58) | NPC1LMNAACHESMN1; SMN2NPSR1 | |
| SCHEMBL10746309 | 0.78 | PBRM1 (0.46) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL3134419 | 0.77 | CES1 (0.60) | POLBACHEHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL21509990 | 0.77 | PARP1 (0.64) | NPC1LMNASMN1; SMN2NPSR1PRSS1 | |
| SCHEMBL9115535 | 0.75 | LMNA (0.44) | NPC1LMNAPOLBPTGS1F2 | |
| SCHEMBL29841359 | 0.75 | PBRM1 (0.61) | PBRM1NPC1MITFLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347859-B | Synthesis and Anticancer Activity of Aryl and Heteroaryl Quinoline Derivatives | EFFICIENT PHARMA MANAGEMENT CORP. (CN) | 2015-12-02 | — | — | CN | disclosed |