Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176747 | 0.84 | LMNA (0.45) | LMNACYP1A2CYP3A4MAPTMAOA | |
| SCHEMBL4877049 | 0.82 | LMNA (0.44) | LMNACYP1A2CYP3A4MAPTMAOA | |
| SCHEMBL7991415 | 0.82 | CA2 (0.59) | LMNAMAPTNPC1RAB9AMEN1 | |
| SCHEMBL3128827 | 0.80 | CES2 (0.50) | LMNACYP1A2MAPTNPC1RAB9A | |
| SCHEMBL5698489 | 0.80 | CES1 (0.50) | CYP1A2MAPTNPC1RAB9ACA2 | |
| SCHEMBL4876868 | 0.80 | LMNA (0.42) | LMNACYP1A2CYP3A4MAPTMAOA | |
| SCHEMBL1851024 | 0.79 | CES1 (0.60) | LMNAAPEX1MEN1POLBPKM | |
| SCHEMBL3134419 | 0.79 | CES1 (0.60) | CYP3A4MAPTPOLBKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL317255 | 0.78 | CES2 (0.48) | LMNAMAPTNPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL28253028 | 0.77 | CES1 (0.58) | LMNAAPEX1MEN1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482508-B1 | Biscationic azo dyes and their intermediates | BASF AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| US-5424404-A | Colorfastness, discoloration inhibition, red and yellow color; coloring paper, leather, printing on polymeric material | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0482508-A1 | Biscationic azo dyes and their intermediates | BASF Aktiengesellschaft (DE) | 1992-04-29 | — | — | EP | disclosed |