SCHEMBL2803982

SCHEMBL2803982

CC(C)(C)C1=CC(=C(c2ccccc2)c2ccccc2)[C]=C1

nearest known ligand 0.30

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.30
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30
SETD7 Q8WTS6 1/20 0.30
LMNA P02545 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
HTR2A P28223 1/20 0.30
HRH1 P35367 1/20 0.30
HTR2B P41595 1/20 0.30
CHRNA4 P43681 1/20 0.30
HTR3A P46098 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7107243 0.69 ATM (0.35) L3MBTL1SETD7LMNA
SCHEMBL2274381 0.67 TDP1 (0.39) TDP1MAPTL3MBTL1ALDH1A1TSHR
SCHEMBL6225156 0.64 KCNK9 (0.40) TDP1MAPTL3MBTL1ALDH1A1LMNA
SCHEMBL398096 0.62 ATM (0.35) TDP1SETD7LMNACYP2D6
SCHEMBL29851581 0.59 ATM (0.35) TDP1MAPTL3MBTL1ALDH1A1TSHR
SCHEMBL1903673 0.59 CA2 (0.33) TDP1MAPTL3MBTL1ALDH1A1TSHR
SCHEMBL31729517 0.58 POLB (0.46) TDP1MAPTL3MBTL1ALDH1A1TSHR
SCHEMBL8501035 0.57 DAO (0.30) ALDH1A1TSHR
SCHEMBL11844374 0.56 ESR1 (0.56) TDP1MAPTL3MBTL1ALDH1A1TSHR
SCHEMBL1035354 0.56 ESR1 (0.56) TDP1MAPTL3MBTL1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785574-B2 Bridged metallocene compound, olefin polymerization catalyst containing the same, and ethylene polymer obtained with the catalyst MITSUI CHEMICALS, INC. (JP) 2014-07-22 US disclosed
US-20140114031-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST PRIME POLYMER CO., LTD. (JP) 2014-04-24 US disclosed
EP-2218725-B1 BRIDGED METALLOCENE OLEFIN POLYMERIZATION CATALYST AND ETHYLENE POLYMER OBTAINED BY USING THE CATALYST MITSUI CHEMICALS INC (JP) 2013-10-23 EP disclosed
US-20100292421-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST MITSUI CHEMICALS, INC. 2010-11-18 US disclosed
EP-2218725-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST USING THE COMPOUND AND ETHYLENE POLYMER OBTAINED BY USING THE CATALYST Mitsui Chemicals, Inc. (JP) 2010-08-18 EP disclosed
US-7737239-B2 Propylene copolymer, polypropylene composition and uses thereof, transition metal compound and olefin polymerization catalyst MITSUI CHEMICALS, INC. (JP) 2010-06-15 US disclosed
EP-1988104-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-03-03 EP disclosed
EP-1985637-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-03-03 EP disclosed
EP-1985638-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-02-17 EP disclosed
US-20080306234-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION AND USES THEREOF, TRANSITION METAL COMPOUND AND OLEFIN POLYMERIZATION CATALYST IKENAGA SHIGENOBU 2008-12-11 US disclosed
EP-1988104-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-11-05 EP disclosed
EP-1985637-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1985638-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1614699-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION Mitsui Chemicals, Inc. (JP) 2006-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292421-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST CAD, ENDOD1, CCT7 TDP1 333/4885MAPT 321/4885L3MBTL1 972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.