Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040033 | 0.89 | ALOX5 (0.35) | BLMALDH1A1NR1D1HPGDKDM4E | |
| SCHEMBL28040541 | 0.80 | ALDH1A1 (0.38) | ALDH1A1HPGDALOX5 | |
| SCHEMBL1680352 | 0.74 | ALOX5 (0.42) | ALDH1A1HPGDKDM4EALOX5EPHX2 | |
| SCHEMBL28040538 | 0.72 | CYP2A6 (0.42) | PPARAPPARDPPARG | |
| SCHEMBL1817057 | 0.68 | BLM (0.71) | BLMALDH1A1HPGDKDM4ERIPK1 | |
| SCHEMBL9079628 | 0.68 | BLM (0.71) | BLMALDH1A1HPGDKDM4ERIPK1 | |
| SCHEMBL1817058 | 0.68 | BLM (0.71) | BLMALDH1A1HPGDKDM4ERIPK1 | |
| SCHEMBL15898183 | 0.67 | ALDH1A1 (0.42) | ALDH1A1KDM4EDPP4 | |
| SCHEMBL21850342 | 0.67 | HPGD (0.46) | PPARAPPARDPPARGHPGDKDM4E | |
| SCHEMBL23430239 | 0.67 | HPGD (0.46) | BLMMMEACEHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175392-B | A kind of carboxylic acid compound containing thiophene-structure and amide compound containing thiophene-structure and preparation method thereof | 湖南大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-105175392-A | Carboxylic acid compounds containing thiophene structures and amide compounds containing thiophene structures and preparation method for carboxylic acid compounds and amide compounds | UNIV HUNAN | 2015-12-23 | — | — | CN | disclosed |