Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040036 | 0.80 | PPARA (0.36) | ALDH1A1ALOX5HPGD | |
| SCHEMBL28040033 | 0.79 | ALOX5 (0.35) | ALDH1A1ALOX5HPGD | |
| SCHEMBL1680352 | 0.77 | ALOX5 (0.42) | ALDH1A1ADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL9192828 | 0.73 | ALDH1A1 (0.50) | ALDH1A1ADRA1DADRA1AADRA1BHPGD | |
| SCHEMBL15898183 | 0.70 | ALDH1A1 (0.42) | ALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL7043843 | 0.69 | LOXL2 (0.40) | LMNATP53HPGD | |
| SCHEMBL15898515 | 0.68 | ALDH1A1 (0.45) | ALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL4661245 | 0.68 | CYP3A4 (0.46) | ALDH1A1LMNAHPGD | |
| SCHEMBL7042751 | 0.67 | HPGD (0.39) | LMNATP53HPGD | |
| SCHEMBL28040062 | 0.66 | LMNA (0.33) | ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175392-A | Carboxylic acid compounds containing thiophene structures and amide compounds containing thiophene structures and preparation method for carboxylic acid compounds and amide compounds | UNIV HUNAN | 2015-12-23 | — | — | CN | disclosed |