Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040036 | 0.89 | PPARA (0.36) | ALOX5EPHX2ALDH1A1HPGDKDM4E | |
| Quinoline SCHEMBL29290749 | 0.86 | ENPP2 (0.33) | — | |
| SCHEMBL28040541 | 0.79 | ALDH1A1 (0.38) | ALOX5ALDH1A1HPGD | |
| SCHEMBL28040728 | 0.73 | CYP2A6 (0.41) | ALOX5EPHX2 | |
| SCHEMBL1680352 | 0.73 | ALOX5 (0.42) | ALOX5EPHX2ALDH1A1HPGDKDM4E | |
| SCHEMBL3832104 | 0.70 | KCNN4 (0.48) | ALDH1A1HPGDKCNN4KDM4EBLM | |
| SCHEMBL9192828 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EDPP4 | |
| SCHEMBL28040597 | 0.67 | CHRM3 (0.39) | ALOX5KCNN4KDM4EBLM | |
| SCHEMBL21850342 | 0.66 | HPGD (0.46) | HPGDKDM4EDPP4RIPK1 | |
| SCHEMBL15898183 | 0.66 | ALDH1A1 (0.42) | ALDH1A1KDM4EDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175392-A | Carboxylic acid compounds containing thiophene structures and amide compounds containing thiophene structures and preparation method for carboxylic acid compounds and amide compounds | UNIV HUNAN | 2015-12-23 | — | — | CN | disclosed |