Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 14/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358276 | 0.84 | KIF11 (0.46) | KIF11CYP1A2CYP2D6DNMT1 | |
| SCHEMBL934496 | 0.72 | CYP2D6 (0.46) | KIF11CYP1A2CYP2D6DNMT1 | |
| SCHEMBL27911897 | 0.72 | CYP1A2 (0.42) | KIF11CYP1A2CYP2D6DNMT1 | |
| SCHEMBL28438065 | 0.71 | CYP1A2 (0.39) | ALDH1A1PKMCYP1A2CYP2D6 | |
| SCHEMBL11258582 | 0.69 | MME (0.44) | — | |
| SCHEMBL31091500 | 0.68 | KIF11 (0.43) | KIF11CYP1A2CYP2D6DNMT1 | |
| SCHEMBL4840669 | 0.68 | KIF11 (0.43) | KIF11CYP1A2CYP2D6DNMT1 | |
| SCHEMBL1906466 | 0.67 | MEN1 (0.34) | ALDH1A1PKMSLC1A2 | |
| SCHEMBL11194318 | 0.67 | ALDH1A1 (0.50) | ALDH1A1PKMSLC1A2CYP1A2 | |
| SCHEMBL2772327 | 0.66 | KIF11 (0.48) | KIF11CYP1A2CYP2D6DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981251-A | Insulin analog dimers | UNIV INDIANA RES & TECH CORP | 2015-10-14 | — | — | CN | disclosed |