Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 10/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.45 |
| ▸ | RXRA | P19793 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30595864 | 0.82 | RIPK1 (0.53) | NR1H2NR1H3RXRAKDM4EALDH1A1 | |
| SCHEMBL2640496 | 0.81 | NR1H2 (0.45) | NR1H2NR1H3RXRAGPR119 | |
| SCHEMBL4325057 | 0.80 | NR1H2 (0.49) | NR1H2NR1H3RXRAGPR119 | |
| SCHEMBL22285173 | 0.80 | NR1H2 (0.49) | NR1H2NR1H3RXRAGPR119 | |
| SCHEMBL874416 | 0.80 | NR1H2 (0.49) | NR1H2NR1H3RXRAGPR119 | |
| SCHEMBL3201139 | 0.79 | NR1H2 (0.44) | NR1H2NR1H3RXRA | |
| SCHEMBL16835137 | 0.76 | ALOX12 (0.59) | HRH3KDM4EGPR119 | |
| SCHEMBL3697218 | 0.75 | DPP4 (0.47) | NR1H2NR1H3 | |
| SCHEMBL25913721 | 0.75 | DPP4 (0.47) | NR1H2NR1H3 | |
| SCHEMBL28371859 | 0.75 | GPR119 (0.46) | KDM4EALDH1A1GPR119LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459258-B | Preparation and use of 1,2, 4-triazolo [1,5a ] pyridine derivatives | CEPHALON, INC. (US) | 2015-11-25 | — | — | CN | disclosed |