SCHEMBL28040360

SCHEMBL28040360

[CH2]c1ccc(C)c(C)c1C.[MgH2]

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.33
CYP2A6 P11509 1/20 0.33
TSHR P16473 1/20 0.33
TDP2 O95551 1/20 0.33
NSD2 O96028 1/20 0.33
HSP90AA1 P07900 1/20 0.33
PAX8 Q06710 1/20 0.33
POLB P06746 1/20 0.31
TRPA1 O75762 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394867 0.97 CYP1A2 (0.35) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL11464954 0.84 ACHE (0.33) TSHR
Ethylene SCHEMBL27743172 0.77 TSHR (0.41) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL29352563 0.77 TSHR (0.45) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL37955 0.77 TSHR (0.45) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL5494672 0.77 TSHR (0.45) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL10592780 0.77 POLB (0.31) CYP1A2POLB
SCHEMBL7612449 0.77 CYP1A2 (0.33) CYP1A2CYP2A6TSHRTDP2NSD2
Formaldehyde SCHEMBL27505936 0.74 TDP2 (0.46) CYP1A2CYP2A6TSHRTDP2NSD2
Bromide SCHEMBL29115028 0.73 TSHR (0.43) CYP1A2CYP2A6TSHRTDP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102666561-B Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-11-25 CN disclosed