Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395136 | 0.97 | RAPGEF4 (0.39) | RAPGEF4ACHEALDH1A1KDM4ELMNA | |
| SCHEMBL3641181 | 0.76 | ALDH1A1 (0.52) | RAPGEF4ACHEALDH1A1KDM4ELMNA | |
| SCHEMBL28951 | 0.75 | RAPGEF4 (0.59) | RAPGEF4ACHEALDH1A1KDM4ELMNA | |
| SCHEMBL1551822 | 0.75 | RAPGEF4 (0.59) | RAPGEF4ACHEALDH1A1KDM4ELMNA | |
| SCHEMBL28040434 | 0.74 | — | — | |
| SCHEMBL28040386 | 0.73 | RAPGEF4 (0.43) | RAPGEF4ACHEALDH1A1KDM4ELMNA | |
| SCHEMBL5180888 | 0.72 | RAPGEF4 (0.56) | RAPGEF4ACHEALDH1A1KDM4ELMNA | |
| SCHEMBL28482658 | 0.72 | RAPGEF4 (0.56) | RAPGEF4ACHEALDH1A1KDM4ELMNA | |
| SCHEMBL10412763 | 0.72 | RAPGEF4 (0.56) | RAPGEF4ACHEALDH1A1KDM4ELMNA | |
| SCHEMBL2809409 | 0.71 | ACHE (0.50) | ACHEALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |