SCHEMBL395136

SCHEMBL395136

[CH2]c1cc(C)cc(C)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 5/20 0.39
ACHE P22303 1/20 0.35
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30
GRIN2D O15399 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28040382 0.97 RAPGEF4 (0.38) RAPGEF4ACHEALDH1A1KDM4ELMNA
SCHEMBL3641181 0.78 ALDH1A1 (0.52) RAPGEF4ACHEALDH1A1KDM4ELMNA
SCHEMBL28951 0.77 RAPGEF4 (0.59) RAPGEF4ACHEALDH1A1KDM4ELMNA
SCHEMBL1551822 0.77 RAPGEF4 (0.59) RAPGEF4ACHEALDH1A1KDM4ELMNA
SCHEMBL5180888 0.74 RAPGEF4 (0.56) RAPGEF4ACHEALDH1A1KDM4ELMNA
SCHEMBL28482658 0.74 RAPGEF4 (0.56) RAPGEF4ACHEALDH1A1KDM4ELMNA
SCHEMBL10412763 0.74 RAPGEF4 (0.56) RAPGEF4ACHEALDH1A1KDM4ELMNA
SCHEMBL2809409 0.73 ACHE (0.50) ACHEALDH1A1KDM4ELMNAGAA
SCHEMBL395776 0.73
SCHEMBL16196856 0.72 RAPGEF4 (0.36) RAPGEF4ALDH1A1KDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3904360-B1 NOVEL TETRAARYLBORATE COMPOUND, CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME SABIC SK NEXLENE COMPANY PTE LTD (SG) 2024-07-03 EP disclosed
CN-113677686-B Novel tetraarylborate compounds, catalyst compositions comprising the same, and process for preparing ethylene homopolymers or copolymers of ethylene and alpha-olefins by using the same 沙特基础工业爱思开NEXLENE私人有限公司 2024-06-11 CN disclosed
CN-113387055-B Film, method for producing film, and bag 住友化学株式会社 2024-06-07 CN disclosed
CN-117425653-A Method for producing bipyridine derivative, method for producing macrocyclic compound, method for producing metal complex containing macrocyclic compound as ligand, metal complex, electrode for air battery, and air battery 住友化学株式会社 2024-01-19 CN disclosed
CN-111148748-B Novel indene-based transition metal compound, transition metal catalyst composition comprising the same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using the same 沙特基础工业爱思开NEXLENE私人有限公司 2023-05-16 CN disclosed
US-11643533-B2 Film, method of producing film, and bag SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-09 US disclosed
CN-112638997-B Film and packaging container 住友化学株式会社 2023-04-28 CN disclosed
WO-2022249992-A1 PRODUCTION METHOD FOR BIPYRIDINE DERIVATIVE, PRODUCTION METHOD FOR MACROCYCLIC COMPOUND, PRODUCTION METHOD FOR METAL COMPLEX INCLUDING MACROCYCLIC COMPOUND AS LIGAND, METAL COMPLEX, ELECTRODE FOR AIR BATTERY, AND AIR BATTERY 住友化学株式会社 2022-12-01 WO disclosed
CN-110352213-B Film 住友化学株式会社 2022-09-09 CN disclosed
CN-114391029-A Electrical connectors formed from polymer compositions having low dielectric constants and dissipation factors 提克纳有限责任公司 2022-04-22 CN disclosed
US-5155113-A Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-10-13 US disclosed
EP-0180188-B1 A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-04-15 EP disclosed
EP-0436902-A1 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-07-17 EP disclosed
US-4983609-A Anticancer agents OTSUKA PHARMACEUTICAL (JP) 1991-01-08 US disclosed
US-4864021-A ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-09-05 US disclosed
EP-0323441-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0180897-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-14 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed
EP-0074132-B1 PROTECTION OF CROPS AGAINST SOIL PESTS EMPLOYING AN ALKYLBENZYL CYCLOPROPANE CARBOXYLATE, NOVEL CYCLOPROPANE CARBOXYLATES, AND COMPOSITIONS CONTAINING THEM SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-04-30 EP disclosed
EP-0074132-A1 Protection of crops against soil pests employing an alkylbenzyl cyclopropane carboxylate, novel cyclopropane carboxylates, and compositions containing them SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-03-16 EP disclosed