Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040420 | 0.80 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3NPC1 | |
| SCHEMBL439492 | 0.78 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3NPC1 | |
| SCHEMBL27870094 | 0.74 | MEN1 (0.35) | ESR1ESR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27886362 | 0.73 | TP53 (0.36) | ESR1ESR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27376874 | 0.73 | RAB9A (0.38) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL28226563 | 0.70 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL28912 | 0.67 | ESR1 (0.50) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL5607685 | 0.67 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3NPC1 | |
| SCHEMBL31290736 | 0.67 | MEN1 (0.57) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL271787 | 0.67 | ESR1 (0.50) | ESR1ESR2NR1H2NR1H3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |