Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942555 | 0.80 | HSD11B1 (0.39) | CA2CA1HPGDALDH1A1HSD17B10 | |
| SCHEMBL28040433 | 0.80 | PTGS2 (0.38) | ALDH1A1HSD17B10TP53ESR1ADRA2A | |
| SCHEMBL27942534 | 0.79 | CA2 (0.38) | CA2CA1HPGDALDH1A1HSD17B10 | |
| SCHEMBL27953365 | 0.79 | CA2 (0.38) | CA2CA1HPGDALDH1A1HSD17B10 | |
| SCHEMBL28040859 | 0.77 | CA2 (0.36) | CA2CA1HPGDALDH1A1HSD17B10 | |
| SCHEMBL28040720 | 0.74 | CA2 (0.34) | CA2CA1HPGDALDH1A1HSD17B10 | |
| SCHEMBL28040390 | 0.74 | — | — | |
| SCHEMBL28040415 | 0.72 | HSPA5 (0.30) | — | |
| SCHEMBL28040850 | 0.70 | CA2 (0.35) | CA2CA1HPGDALDH1A1HSD17B10 | |
| SCHEMBL10321106 | 0.69 | CA2 (0.34) | CA2CA1HPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |