SCHEMBL28040859

SCHEMBL28040859

CCCCc1ccc([Si]([C]2C=CC(C(C)C)=C2)(c2ccc(CCCC)cc2)c2ccc(CCCC)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
UCHL3 P15374 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ESR1 P03372 2/20 0.33
ADRA2A P08913 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
TACR2 P21452 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
HSD11B1 P28845 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
SHBG P04278 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28040720 0.89 CA2 (0.34) CA2CA1UCHL3ALDH1A1HSD17B10
SCHEMBL27942555 0.80 HSD11B1 (0.39) CA2CA1ALDH1A1HSD17B10HPGD
SCHEMBL28808177 0.80 CA2 (0.39) CA2CA1ALDH1A1HSD17B10HPGD
SCHEMBL28040357 0.80 PTGS2 (0.38) ALDH1A1HSD17B10ESR1ADRA2AADORA3
SCHEMBL27942534 0.79 CA2 (0.38) CA2CA1ALDH1A1HSD17B10HPGD
SCHEMBL27953365 0.79 CA2 (0.38) CA2CA1ALDH1A1HSD17B10HPGD
SCHEMBL28040462 0.77 CA2 (0.36) CA2CA1ALDH1A1HSD17B10HPGD
SCHEMBL27886343 0.74
Methylamine SCHEMBL28809730 0.73 CA2 (0.42) CA2CA1ALDH1A1HSD17B10HPGD
SCHEMBL28040832 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102666561-B Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-11-25 CN disclosed
CN-102666607-B Olefinic polymers SUMITOMO CHEMICAL CO 2014-03-26 CN disclosed