Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 13/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588721 | 0.86 | CASP6 (0.60) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL8092214 | 0.83 | CASP6 (0.64) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL27411911 | 0.81 | CASP6 (0.62) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL5913447 | 0.81 | CASP6 (0.62) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL6180268 | 0.81 | HCAR3 (0.64) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL30481076 | 0.81 | CASP6 (0.66) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL20757 | 0.81 | PDK1 (0.68) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL1483517 | 0.81 | CASP6 (0.66) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL6341472 | 0.81 | CASP6 (0.66) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL1251308 | 0.80 | CASP6 (0.64) | CASP6TSHRLMNAHCAR3APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228982-B | 3-acetylamino-1- (phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino) benzene derivatives for the treatment of hyperproliferative disorders | 拜耳制药股份公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-105579457-B | Substituted N-biphenyl-3-acetylamino-benzamides and N- [3- (acetylamino) phenyl ] -biphenyl-carboxamides and their use as WNT signaling pathway inhibitors | 拜耳制药股份公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-105579457-A | Substituted N-biphenyl-3-acetylamino-benzamides and N- [3- (acetylamino) phenyl ] -biphenyl-carboxamides and their use as WNT signaling pathway inhibitors | Bayer Pharma AG | 2016-05-11 | — | — | CN | disclosed |
| CN-105228982-A | 3-acetylamino-1- (phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino) benzene derivatives for the treatment of hyperproliferative disorders | Bayer Pharma AG | 2016-01-06 | — | — | CN | disclosed |