Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12921070 | 0.88 | CA12 (0.50) | MAPTPPARANPSR1HPGDPOLB | |
| SCHEMBL979301 | 0.84 | ELANE (0.41) | MAPTPPARAPPARGTDP1KDM4E | |
| SCHEMBL28456642 | 0.81 | MAPT (0.54) | MAPTTDP1KDM4EPTK2BRAB9A | |
| SCHEMBL6125235 | 0.81 | MAPT (0.50) | MAPTTDP1KDM4EPTK2BRAB9A | |
| SCHEMBL12921072 | 0.81 | HPGD (0.53) | MAPTPPARAPPARGTDP1KDM4E | |
| SCHEMBL47951 | 0.78 | L3MBTL1 (0.48) | MAPTTDP1KDM4ENPSR1HSD17B10 | |
| SCHEMBL11876281 | 0.78 | PPARA (0.50) | MAPTPPARAPPARGHPGDKMT2A | |
| SCHEMBL2873451 | 0.78 | SLC6A3 (0.44) | MAPTPPARAPPARGTDP1KDM4E | |
| SCHEMBL3908751 | 0.75 | MAPT (0.42) | MAPTPPARAPPARGTDP1ALDH1A1 | |
| SCHEMBL16301776 | 0.75 | PPARA (0.42) | MAPTPPARAPPARGTDP1PTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214409-B | The synthesis of tsiklomitsin and analogue thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-21 | — | — | CN | disclosed |