SCHEMBL2873451

SCHEMBL2873451

CCc1ccccc1-c1cccc(OC(=O)O)c1C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.44
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
HDAC1 Q13547 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
PPARA Q07869 3/20 0.40
PPARG P37231 2/20 0.40
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TSHR P16473 2/20 0.40
FGFR1 P11362 1/20 0.39
SRC P12931 1/20 0.39
FGFR2 P21802 1/20 0.39
FGFR4 P22455 1/20 0.39
FGFR3 P22607 1/20 0.39
HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5710937 0.83 HTT (0.51) SLC6A3CA12CA1CA2CA7
SCHEMBL1838337 0.79 PLA2G2A (0.39) PPARAPPARGL3MBTL1FGFR1SRC
SCHEMBL1839977 0.78 LTB4R (0.40) PPARAPPARGNCEH1
SCHEMBL4657202 0.78 SLC6A3 (0.50) SLC6A3CA12CA1CA2CA7
SCHEMBL28040667 0.78 MAPT (0.44) PPARAPPARGTSHRKDM4EHSD17B10
SCHEMBL47951 0.77 L3MBTL1 (0.48) L3MBTL1TSHRKDM4EHSD17B10ALDH1A1
SCHEMBL30148050 0.77 HTT (0.51) CA12CA1CA2CA7CA9
SCHEMBL17698893 0.77 KMT2A (0.41) PPARAL3MBTL1HTTKDM4EHSD17B10
SCHEMBL1842589 0.76 PPARA (0.43) PPARAPPARGNCEH1KDM4E
SCHEMBL27552871 0.76 HTT (0.45) GAAL3MBTL1FGFR1SRCFGFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1724110-B1 Multilayered articles and method of manufacture thereof SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-08-21 EP disclosed
US-8900693-B2 Polycarbonate compositions having infrared absorbance, method of manufacture, and articles prepared therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2014-12-02 US disclosed
EP-1907465-B1 POLYCARBONATE COMPOSITIONS HAVING INFRARED ABSORBANCE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2014-07-23 EP disclosed
EP-1529632-B1 Multilayered articles and method of manufacture thereof SABIC INNOVATIVE PLASTICS IP (NL) 2012-09-05 EP disclosed
EP-2202063-A2 Multilayered articles and method of manufacture thereof Sabic Innovative Plastics IP B.V. (NL) 2010-06-30 EP disclosed
EP-1559743-B1 Infra-red radiation absorption articles and method of manufacturing thereof SABIC INNOVATIVE PLASTICS IP (NL) 2009-02-18 EP disclosed
EP-1996650-A2 FLAME RETARDANT POLYCARBONATE COMPOSITIONS HAVING GOOD TRANSPARENCY AND LOW HAZE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2008-12-03 EP disclosed
US-7399571-B2 Multilayered articles and method of manufacture thereof GENERAL ELECTRIC COMPANY (US) 2008-07-15 US disclosed
EP-1907465-A2 POLYCARBONATE COMPOSITIONS HAVING INFRARED ABSORBANCE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM General Electric Company (US) 2008-04-09 EP disclosed
WO-2008013579-A2 FLAME RETARDANT POLYCARBONATE COMPOSITIONS HAVING GOOD TRANSPARENCY AND LOW HAZE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-31 WO disclosed
WO-2005087008-A2 BIOCIDAL COMPOSITIONS AND METHODS OF MAKING THEREOF GENERAL ELECTRIC COMPANY (US) 2005-09-22 WO disclosed
US-20050203237-A1 Biocidal compositions and methods of making thereof CITIBANK, N.A., AS COLLATERAL AGENT 2005-09-15 US disclosed
US-20050202100-A1 Biocidal compositions and methods of making thereof CITIBANK, N.A., AS COLLATERAL AGENT 2005-09-15 US disclosed
WO-2005075550-A1 INFRA-RED RADIATION ABSORPTION ARTICLES AND METHOD OF MANUFACTURE THEREOF GENERAL ELECTRIC COMPANY (US) 2005-08-18 WO disclosed
EP-1559743-A1 Infra-red radiation absorption articles and method of manufacturing thereof GENERAL ELECTRIC COMPANY (US) 2005-08-03 EP disclosed
US-20050165148-A1 Infra-red radiation absorption articles and method of manufacture thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-07-28 US disclosed
WO-2005053953-A1 MULTIWALL SHEETS AND METHODS FOR MANUFACTURING THEREOF GENERAL ELECTRIC COMPANY (US) 2005-06-16 WO disclosed
US-20050112331-A1 Multiwall sheets and methods for manufacturing thereof GENERAL ELECTRIC COMPANY 2005-05-26 US disclosed
EP-1529632-A1 Multilayered articles and method of manufacture thereof GENERAL ELECTRIC COMPANY (US) 2005-05-11 EP disclosed
US-4323668-A (Ortho-alkoxycarbonyaryl)-carbonate transesterification GENERAL ELECTRIC COMPANY (US) 1982-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050202100-A1 Biocidal compositions and methods of making thereof PIK3C3, PRKACG, PRKX SLC6A3 3658/4885CA12 3087/4885CA1 609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.