Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 8/20 | 0.37 |
| ▸ | NOS2 | P35228 | 8/20 | 0.37 |
| ▸ | NOS3 | P29474 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040833 | 0.82 | PNMT (0.35) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL28040497 | 0.81 | PNMT (0.34) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL28040417 | 0.80 | PNMT (0.33) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| Methylamine SCHEMBL28040876 | 0.79 | PNMT (0.40) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL28040356 | 0.77 | TLR8 (0.36) | PNMTENPP2 | |
| SCHEMBL28040862 | 0.77 | PNMT (0.32) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL28040801 | 0.75 | PNMT (0.37) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL27870082 | 0.74 | LMNA (0.31) | — | |
| SCHEMBL28040373 | 0.73 | HDAC4 (0.34) | ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL28040831 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |