Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.39 |
| ▸ | NOS1 | P29475 | 10/20 | 0.38 |
| ▸ | NOS2 | P35228 | 10/20 | 0.38 |
| ▸ | NOS3 | P29474 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040769 | 0.79 | NOS1 (0.37) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL1908526 | 0.77 | PNMT (0.48) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL28040833 | 0.76 | PNMT (0.35) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL28040801 | 0.76 | PNMT (0.37) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL28040497 | 0.75 | PNMT (0.34) | PNMTENPP2LOXL2NOS1NOS2 | |
| Methylamine SCHEMBL27942526 | 0.73 | ESR1 (0.32) | — | |
| Methylamine SCHEMBL28040840 | 0.72 | HDAC4 (0.36) | ALDH1A1SMN1; SMN2CYP3A4 | |
| Methylamine SCHEMBL28040721 | 0.71 | NOS3 (0.31) | NOS1NOS2NOS3 | |
| SCHEMBL27938953 | 0.71 | PNMT (0.45) | PNMTENPP2LOXL2NOS1NOS2 | |
| SCHEMBL15981410 | 0.71 | ENPP2 (0.50) | PNMTENPP2LOXL2NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |