Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040417 | 0.92 | PNMT (0.33) | TLR8TLR7PNMTENPP2 | |
| SCHEMBL27886277 | 0.80 | HSD11B1 (0.33) | TLR8LIPG | |
| SCHEMBL28040464 | 0.79 | CTSS (0.33) | — | |
| SCHEMBL28040817 | 0.77 | NPC1 (0.32) | XIAP | |
| SCHEMBL28040769 | 0.77 | NOS1 (0.37) | PNMTENPP2 | |
| SCHEMBL28808177 | 0.76 | CA2 (0.39) | LPLLIPGSKP2 | |
| SCHEMBL28040833 | 0.75 | PNMT (0.35) | PNMTENPP2 | |
| SCHEMBL28040799 | 0.75 | PTGS2 (0.40) | LPLLIPG | |
| SCHEMBL28040497 | 0.74 | PNMT (0.34) | PNMTENPP2 | |
| SCHEMBL28040378 | 0.74 | TLR8 (0.36) | TLR8TLR7PNMTENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |