Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.75 |
| ▸ | NPC1 | O15118 | 2/20 | 0.75 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963658 | 0.87 | HPGD (0.64) | RAB9ANPC1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL29893391 | 0.85 | HPGD (0.61) | RAB9ANPC1HPGDSMN1; SMN2HDAC6 | |
| SCHEMBL4902871 | 0.85 | RAB9A (0.64) | RAB9ANPC1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL397896 | 0.84 | NPC1 (0.67) | RAB9ANPC1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL401620 | 0.82 | RAB9A (0.62) | RAB9ANPC1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL25977894 | 0.82 | GABRG2 (0.51) | RAB9ANPC1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL17184512 | 0.82 | NPC1 (0.64) | RAB9ANPC1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL9939451 | 0.82 | HPGD (0.64) | RAB9ANPC1HPGDMAPTKMT2A | |
| SCHEMBL26613609 | 0.81 | ALOX15 (0.57) | RAB9ANPC1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL29437732 | 0.81 | ALOX15 (0.57) | RAB9ANPC1HPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103702985-B | As CRTH 2the quinoxaline of receptor modulators and azaquinoxaline | MERCK SHARP & DOHME CORP. (US) | 2016-02-17 | — | — | CN | disclosed |
| CN-102656163-B | Suppress the heterogeneous ring compound of PASK | BIOENERGENIX (US) | 2016-01-13 | — | — | CN | disclosed |