Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.64 |
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 11/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041343 | 0.85 | RAB9A (0.75) | RAB9AMAPTKMT2AMEN1NPSR1 | |
| SCHEMBL9939339 | 0.82 | HPGD (0.57) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL18883004 | 0.82 | KMT2A (0.57) | RAB9AMAPTKMT2AMEN1NPSR1 | |
| SCHEMBL30965453 | 0.82 | HPGD (0.57) | RAB9AMAPTKMT2AMEN1NPSR1 | |
| SCHEMBL9939451 | 0.82 | HPGD (0.64) | RAB9AMAPTKMT2AMEN1HPGD | |
| SCHEMBL25045589 | 0.82 | HPGD (0.57) | RAB9AMAPTKMT2AMEN1NPSR1 | |
| SCHEMBL26613499 | 0.81 | ALDH1A1 (0.60) | RAB9AMAPTKMT2AMEN1KDM4E | |
| SCHEMBL27963658 | 0.80 | HPGD (0.64) | RAB9AMAPTKMT2AMEN1HPGD | |
| SCHEMBL8018992 | 0.80 | ALDH1A1 (0.60) | RAB9AMAPTNPSR1KDM4EALDH1A1 | |
| SCHEMBL28574625 | 0.79 | CYP1A2 (0.56) | RAB9AMAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658930-A | Asymmetric hydrogenation synthesis method of tetrahydroquinoxaline derivative | 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) | 2024-03-08 | — | — | CN | disclosed |
| CN-117568821-A | Electrochemical synthesis method of quinoxaline derivative | 齐齐哈尔医学院 | 2024-02-20 | — | — | CN | disclosed |
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | UNIVERSITY OF OTTAWA | 2008-06-05 | — | — | US | disclosed |
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | UNIVERSITY OF OTTAWA | 2008-06-05 | — | — | US | disclosed |
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | UNIVERSITY OF OTTAWA | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132698-A1 | Use of N-oxide compounds in coupling reactions | CYP4X1, CYP4F3, CYP1A2 | RAB9A 1209/4885MAPT 4072/4885KMT2A 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.