Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CFD | P00746 | 1/20 | 0.58 |
| ▸ | MITF | O75030 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030342 | 0.85 | CFD (0.60) | CFDMAPK1MAPTGAAAURKB | |
| SCHEMBL2636652 | 0.85 | NPSR1 (0.61) | NPSR1MITFALDH1A1HTTMAPK1 | |
| SCHEMBL11802189 | 0.84 | ALDH1A1 (0.67) | NPSR1MITFALDH1A1HTTMAPK1 | |
| SCHEMBL4003071 | 0.83 | MAPT (0.66) | NPSR1MITFALDH1A1HTTMAPK1 | |
| SCHEMBL27641823 | 0.83 | CFD (0.58) | CFDMAPK1MAPTGAAAURKB | |
| SCHEMBL4599573 | 0.83 | RAB9A (0.63) | CFDALDH1A1MAPK1POLBMAPT | |
| SCHEMBL27580045 | 0.82 | NPC1 (0.59) | NPSR1MITFALDH1A1HTTMAPT | |
| SCHEMBL4007324 | 0.82 | NPSR1 (0.66) | NPSR1MITFALDH1A1HTTMAPK1 | |
| SCHEMBL27822593 | 0.82 | CFD (0.83) | NPSR1CFDALDH1A1HTTMAPK1 | |
| SCHEMBL3003205 | 0.81 | CFD (0.59) | CFDMAPTGAASMN1; SMN2AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237474-A | Preparation method and application of 6-hydroxy-7-arylformylquinolinone compounds | UNIV SHENYANG PHARMACEUTICAL | 2016-01-13 | — | — | CN | disclosed |