Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL28621543 | 0.95 | FFAR1 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Adipic Acid SCHEMBL28041700 | 0.95 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Succinic Acid SCHEMBL28691128 | 0.87 | KMT2A (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Toluene SCHEMBL28462909 | 0.87 | LMNA (0.50) | MAPTSMN1; SMN2KMT2AALDH1A1 | |
| Toluene SCHEMBL3469199 | 0.87 | LMNA (0.50) | MAPTSMN1; SMN2KMT2AALDH1A1 | |
| Stearic Acid SCHEMBL27904761 | 0.87 | GPR84 (0.55) | HDAC11MAPTFFAR1GPR84FFAR4 | |
| Adipic Acid SCHEMBL27076123 | 0.85 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Adipic Acid SCHEMBL27076125 | 0.85 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Toluene SCHEMBL326274 | 0.83 | TSHR (0.46) | MAPTSMN1; SMN2KMT2AALDH1A1 | |
| Toluene SCHEMBL26603134 | 0.83 | CAMK2A (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237731-A | Heat-resistant wear-resistant polyurethane material | CHUZHOU HUANQIU POLYURETHANE TECHNOLOGY CO LTD | 2016-01-13 | — | — | CN | claimed |
| CN-105237731-A | Heat-resistant wear-resistant polyurethane material | CHUZHOU HUANQIU POLYURETHANE TECHNOLOGY CO LTD | 2016-01-13 | — | — | CN | disclosed |