Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL28462909 | 1.00 | LMNA (0.50) | LMNAACHETSHRALOX12NPC1 | |
| Toluene SCHEMBL11664184 | 0.93 | LMNA (0.52) | LMNAACHETSHRALOX12NPC1 | |
| Toluene SCHEMBL326274 | 0.91 | TSHR (0.46) | LMNAACHETSHRALOX12NPC1 | |
| Toluene SCHEMBL27294596 | 0.91 | LMNA (0.50) | LMNAACHETSHRALOX12NPC1 | |
| Toluene SCHEMBL28853719 | 0.88 | ACHE (0.65) | LMNAACHETSHRALOX12NPC1 | |
| Toluene SCHEMBL29088577 | 0.88 | ACHE (0.65) | LMNAACHETSHRALOX12NPC1 | |
| Toluene SCHEMBL7745465 | 0.88 | ACHE (0.65) | LMNAACHETSHRALOX12NPC1 | |
| Toluene SCHEMBL28488283 | 0.88 | ACHE (0.65) | LMNAACHETSHRALOX12NPC1 | |
| Toluene SCHEMBL32871 | 0.88 | ACHE (0.65) | LMNAACHETSHRALOX12NPC1 | |
| Toluene SCHEMBL57282 | 0.88 | ACHE (0.65) | LMNAACHETSHRALOX12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192379-A | Lead fluoride | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-03-09 | — | — | US | claimed |
| EP-2055327-B1 | Antimicrobial lubricious coating | COVIDIEN LP (US) | 2013-12-11 | — | — | EP | disclosed |
| US-7820734-B2 | Antimicrobial lubricious coating | TYCO HEALTHCARE GROUP LP (US) | 2010-10-26 | — | — | US | disclosed |
| EP-2055327-A1 | Antimicrobial lubricious coating | Tyco Healthcare Group LP (US) | 2009-05-06 | — | — | EP | disclosed |
| US-20080085949-A1 | ANTIMICROBIAL LUBRICIOUS COATING | KPR U.S., LLC | 2008-04-10 | — | — | US | disclosed |
| US-5192379-A | Lead fluoride | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0106004-B1 | METHOD OF FORMING A HYDROPHILIC COATING ON A SUBSTRATE | Astra Tech Aktiebolag (SE) | 1988-01-07 | — | — | EP | disclosed |
| US-4576156-A | Prophylactic device and method | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-03-18 | — | — | US | disclosed |
| EP-0106004-A1 | Method of forming a hydrophilic coating on a substrate | Astra Tech Aktiebolag (SE) | 1984-04-25 | — | — | EP | disclosed |
| US-RE31340-E | Process for the production of poly (polyisocyanate-polyol-alkali metal silicate) solid | Blount, David H. (US) | 1983-08-09 | — | — | US | disclosed |
| US-4373009-A | Method of forming a hydrophilic coating on a substrate | INTERNATIONAL SILICONE CORPORATION (US) | 1983-02-08 | — | — | US | disclosed |
| US-4296211-A | Process for the production of poly (polyisocyanate-polyol-alkali metal silicate) solid or foamed products | BLOUNT DAVID H | 1981-10-20 | — | — | US | disclosed |
| US-4273908-A | Process for the production of poly (polyisocyanate-polyol-alkali metal silicate solid | BLOUNT DAVID H | 1981-06-16 | — | — | US | disclosed |