Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.50 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15617048 | 0.82 | DYRK1A (0.57) | PARP1IMPDH2ASH1LNR4A2JAK2 | |
| SCHEMBL17179296 | 0.80 | KDM4E (0.55) | PARP1IMPDH2NR4A2KDM4EAR | |
| SCHEMBL28572966 | 0.78 | MAP4K4 (0.42) | PARP1IMPDH2MAP4K4FGFR1KDR | |
| SCHEMBL29539083 | 0.76 | FEN1 (0.56) | PARP1MAP4K4FGFR1KDRMAPK8 | |
| SCHEMBL19893738 | 0.76 | FEN1 (0.56) | PARP1MAP4K4FGFR1KDRMAPK8 | |
| 3-Phenylindole SCHEMBL29609072 | 0.74 | IMPDH2 (0.71) | PARP1IMPDH2PDGFRAASH1LNR4A2 | |
| 3-Phenylindole SCHEMBL84056 | 0.74 | IMPDH2 (0.71) | PARP1IMPDH2PDGFRAASH1LNR4A2 | |
| SCHEMBL2391683 | 0.74 | ALDH1A1 (0.52) | PARP1MAP4K4FGFR1KDRMAPK8 | |
| SCHEMBL28020283 | 0.73 | CCR8 (0.53) | PARP1MAP4K4FGFR1KDRMAPK8 | |
| SCHEMBL21396115 | 0.72 | S1PR1 (0.57) | PARP1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105120863-A | Alkylamine peganine derivatives for promoting bone growth | OSTEOQC INC | 2015-12-02 | — | — | CN | disclosed |