Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346897 | 0.72 | MEN1 (0.36) | HTR2BMEN1LMNATHRBBLM | |
| SCHEMBL28144810 | 0.71 | MEN1 (0.33) | HTR2BMEN1LMNATHRBBLM | |
| SCHEMBL15236205 | 0.70 | IDO1 (0.36) | HTR2BMEN1LMNATHRBBLM | |
| SCHEMBL27741225 | 0.60 | ACHE (0.33) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL11566679 | 0.59 | KMT2A (0.43) | HTR2BMEN1LMNATHRBKMT2A | |
| SCHEMBL22505279 | 0.58 | MEN1 (0.62) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21200769 | 0.55 | MEN1 (0.36) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL11768743 | 0.55 | LMNA (0.60) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL14431153 | 0.55 | MAPT (0.58) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL30497064 | 0.55 | LMNA (0.60) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237440-A | Novel CRAC channel conditioning agent, and preparation method and applications thereof | SHANGHAI INST MATERIA MEDICA | 2016-01-13 | — | — | CN | disclosed |