Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.31 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041735 | 1.00 | ADRB2 (0.36) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28041725 | 0.90 | ADRB2 (0.39) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28041593 | 0.90 | ADRB2 (0.39) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28823976 | 0.86 | — | — | |
| SCHEMBL28041547 | 0.86 | ALDH1A1 (0.33) | ADRB2ADRB1MAPTLMNAMEN1 | |
| SCHEMBL28041531 | 0.83 | ADRB2 (0.40) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28041741 | 0.83 | ADRB2 (0.40) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28990744 | 0.78 | AVPR2 (0.35) | ADRB1AOC3CASP1ATMP2RX7 | |
| SCHEMBL28990603 | 0.78 | AVPR2 (0.35) | ADRB1AOC3CASP1ATMP2RX7 | |
| SCHEMBL28990596 | 0.78 | AVPR2 (0.35) | ADRB1AOC3CASP1ATMP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209027-A | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes | BIO PHARM SOLUTIONS CO LTD | 2015-12-30 | — | — | CN | disclosed |