SCHEMBL28041547

SCHEMBL28041547

COCOCC[C@@H](c1ccccc1F)C(C)(C)OC(N)=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
GAA P10253 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
GNRHR P30968 1/20 0.32
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31
MC4R P32245 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADRB2 P07550 3/20 0.31
ADRB1 P08588 3/20 0.31
ADRB3 P13945 3/20 0.31
MAPT P10636 2/20 0.31
TP53 P04637 1/20 0.31
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28041742 0.90 ALDH1A1 (0.38) ALDH1A1LMNAGAACES2CES1
SCHEMBL28041735 0.86 ADRB2 (0.36) ALDH1A1LMNAMEN1KMT2AADRB2
SCHEMBL28041730 0.86 ADRB2 (0.36) ALDH1A1LMNAMEN1KMT2AADRB2
SCHEMBL28823976 0.86
SCHEMBL28041745 0.83 CES2 (0.37) ALDH1A1LMNAGAACES2CES1
SCHEMBL28990613 0.78 IDO1 (0.38) ALDH1A1LMNAGAACES2CES1
SCHEMBL28990616 0.78 IDO1 (0.38) ALDH1A1LMNAGAACES2CES1
SCHEMBL28990542 0.78 IDO1 (0.38) ALDH1A1LMNAGAACES2CES1
SCHEMBL28041725 0.76 ADRB2 (0.39) ALDH1A1LMNAGAAMEN1KMT2A
SCHEMBL28041593 0.76 ADRB2 (0.39) ALDH1A1LMNAGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105209027-A Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes BIO PHARM SOLUTIONS CO LTD 2015-12-30 CN disclosed